October 2, 2009

Facile Synthesis of 1,2,4-Triazoles via a Copper-Catalyzed Tandem Addition−Oxidative Cyclization

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Abstract

A simple one-step synthesis of 1,2,4-triazole derivatives is provided by a copper-catalyzed oxidative coupling reaction under an atmosphere of air. The process should consist of sequential N-C and N-N bond-forming copper-catalyzed oxidative coupling reactions. Starting materials and the copper catalyst are readily available and inexpensive. A wide range of functional groups are tolerated to achieve chemical diversity.

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Ueda et al. (Fri,) studied this question.

synapsesocial.com/papers/69d74eeac74376700bf3145c https://doi.org/https://doi.org/10.1021/ja905056z

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Journals

Journal of the American Chemical Society

Institutions

Gifu Pharmaceutical University

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Facile Synthesis of 1,2,4-Triazoles via a Copper-Catalyzed Tandem Addition−Oxidative Cyclization

Key Points

Abstract

Citation Network

Connected Papers

Cite This Study

Also Consider

Discussion

Journals

Institutions

References and Citations

Also Consider