What question did this study set out to answer?

Assess the efficacy of adjuvant chemotherapy with the oral fluoropyrimidine S-1 in East Asian patients with locally advanced gastric cancer following D2 dissection.

October 31, 2007New England Journal of MedicineOpen Access

Adjuvant Chemotherapy for Gastric Cancer with S-1, an Oral Fluoropyrimidine

View Full Paper

Ask AI

Bookmark

Authors

SSShinichi SakuramotoSaitama International Medical Center MSMitsuru SasakoYodogawa Christian Hospital TYToshiharu YamaguchiThe Cancer Institute Hospital

Discussion

Member takes

Implication

Randomized trial demonstrates adjuvant S-1 chemotherapy efficacy in locally advanced gastric cancer after D2 dissection, supporting its use as standard postoperative treatment.

Key Points

Assess the efficacy of adjuvant chemotherapy with the oral fluoropyrimidine S-1 in East Asian patients with locally advanced gastric cancer following D2 dissection.
Interventional randomized trial registered under identifier NCT00152217.
Evaluated adjuvant oral fluoropyrimidine S-1 administration in East Asian patients with locally advanced gastric cancer who underwent curative D2 surgical dissection.
Adjuvant S-1 monotherapy is effective in reducing disease recurrence and improving outcomes in East Asian patients following D2 dissection for locally advanced gastric cancer.
Quantitative survival rates, hazard ratios, and confidence intervals were not reported in the abstract text.

Cite This Study

Sakuramoto et al. (2007) studied this question.

synapsesocial.com/papers/69d750edb54ccf0cfef30db1 https://doi.org/10.1056/nejmoa072252

View Full Paper

Ask AI

Bookmark

Implication

Randomized trial demonstrates adjuvant S-1 chemotherapy efficacy in locally advanced gastric cancer after D2 dissection, supporting its use as standard postoperative treatment.

Adjuvant Chemotherapy for Gastric Cancer with S-1, an Oral Fluoropyrimidine

Discussion

Member takes

Implication

Key Points

Cite This Study

Adjuvant Chemotherapy for Gastric Cancer with S-1, an Oral Fluoropyrimidine

Discussion

Member takes

Implication

Key Points

Cite This Study

Also Consider

Also Consider