Female Athletes Genetically Susceptible to Fatigue Fracture Are Resistant to Muscle Injury: Potential Role of COL1A1 Variant

Eri Miyamoto‐Mikami; Hiroshi Kumagai; Kumpei Tanisawa; Yuki Taga; Kosuke Hirata; Naoki Kikuchi; Nobuhiro Kamiya; Ryoko Kawakami; Taishi Midorikawa; Takuji Kawamura; Ryo Kakigi; Toshiharu Natsume; Hirofumi Zempo; Koya Suzuki; Yoshimitsu Kohmura; Kazunori Mizuno; Suguru Torii; Shizuo Sakamoto; Koichiro Oka; Mitsuru Higuchi; Hisashi Naıto; Naokazu Miyamoto; Noriyuki Fuku

doi:10.1249/mss.0000000000002658

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Abstract

The COL1A1 rs1107946 polymorphism exerts antagonistic effects on fatigue fracture and muscle injury among female athletes by altering the properties of these tissues, potentially owing to increased levels of type I collagen α1 chain homotrimers.

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Miyamoto‐Mikami et al. (2021) studied this question.

synapsesocial.com/papers/69d75484aa68b335b4f30fc3 https://doi.org/10.1249/mss.0000000000002658

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Female Athletes Genetically Susceptible to Fatigue Fracture Are Resistant to Muscle Injury: Potential Role of COL1A1 Variant

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Female Athletes Genetically Susceptible to Fatigue Fracture Are Resistant to Muscle Injury: Potential Role of COL1A1 Variant

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