Do pharmacological strategies prevent sudden death in high-risk patients with hypertrophic cardiomyopathy?
Pharmacological strategies lack efficacy for preventing sudden death in high-risk HCM patients, supporting the use of implantable defibrillators as the primary preventive treatment.
Medical treatment is not absolutely protective against the risk of sudden death in HCM. The present data inferentially support the use of the implantable defibrillator as the primary treatment choice for prevention of sudden death in high-risk patients with HCM.
Melacini et al. (Mon,) studied this question.