Neuromyelitis optica spectrum disorder with area postrema syndrome

Neuromyelitis optica spectrum disorders (NMOSD) are autoimmune inflammatory disorders associated with anti-aquaporin 4 (AQP4) antibodies. y clinical features that characterize AP syndrome include intractable hiccups and nausea/vomiting (IHN), as well as lesions on the dorsal tegmentum of the medulla oblongata adjacent to the fourth ventricle visible through MRI. In this report, we describe a patient with NMOSD presenting AP syndrome accompanied with frequent syncope episodes coinciding with cardiac arrest.