Impaired differentiation and cytotoxicity of natural killer cells in systemic lupus erythematosus

This is the authors' abstract. We don't add key points for this paper.

In SLE patients, circulating levels of NK cells were diminished and their cytotoxicities were impaired. Furthermore, the differentiation of HSCs into NK cells was found to be defective. These abnormalities possibly contribute to immune system dysregulation in SLE.