Guideline statement demonstrates updated reporting standards for randomised trial protocols, suggesting improved transparency and completeness across clinical research.
Widespread endorsement and adherence to the updated SPIRIT 2025 statement have the potential to enhance the transparency and completeness of trial protocols for the benefit of investigators, trial participants, patients, funders, research ethics committees, journals, trial registries, policymakers, regulators, and other reviewers.
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Chan et al. (2025) studied this question.
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