Answers are grounded in this paper and cite their sources.
Experimental analysis reveals venous endothelial cells drive vessel expansion and vascular malformations in vascular models, highlighting new therapeutic targets for vascular disorders.
Our studies establish that venous endothelial cells are the primary endothelial subtype responsible for normal expansion of vascular networks, formation of arteriovenous malformations, and pathological angiogenesis. These observations highlight the central role of the venous endothelium in normal development and disease pathogenesis.
No takes yet. Share an insight, caveat, or question.
Lee et al. (2021) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: