Key result
Vascular endothelial cadherin, sphingosine 1-phosphate signaling, and angiopoietin-Tie signaling play critical roles in regulating vascular endothelial cell stabilization and vascular integrity.
This review highlights recent studies on vascular endothelial cadherin, sphingosine 1-phosphate signaling, and angiopoietin-Tie signaling in regulating vascular integrity and angiogenesis.
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Supports pathway targeting in vascular disorders; extends mechanistic insights but leaves open clinical translation.
Naoki Mochizuki (2009) conducted a review in Vascular integrity and angiogenesis. Vascular endothelial cadherin, sphingosine 1-phosphate signaling, and angiopoietin-Tie signaling play critical roles in regulating vascular endothelial cell stabilization and vascular integrity.
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