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May 2, 2012New England Journal of Medicine877 citationsOpen Access

Combination Chemotherapy in Advanced Adrenocortical Carcinoma

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MFMartin FaßnachtMTMassimo TerzoloBABruno Allolio

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Abstract

Rates of response and progression-free survival were significantly better with EDP plus mitotane than with streptozocin plus mitotane as first-line therapy, with similar rates of toxic events, although there was no significant difference in overall survival. (Funded by the Swedish Research Council and others; FIRM-ACT ClinicalTrials.gov number, NCT00094497.).

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Faßnacht et al. (2012) studied this question.

synapsesocial.com/papers/69d76f1cef4aa71f97f31552https://doi.org/10.1056/nejmoa1200966
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