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October 25, 2006The Journal of Clinical Endocrinology & Metabolism

Prognostic Parameters of Metastatic Adrenocortical Carcinoma

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Population

124 consecutive patients with metastatic adrenocortical carcinoma, comprising a main cohort of 70 patients…

Design

Cohort

Authors

GAGuillaume AssiéCentre National de la Recherche ScientifiqueGAGuillemette AntoniInsermFTFrédérique TissierDélégation Paris 5

Discussion

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Implication

May refine prognosis in metastatic adrenocortical carcinoma; leaves open prospective validation before guiding care.

Structured PICO

P
Population
124 consecutive patients with metastatic adrenocortical carcinoma (ACC), comprising a main cohort of 70 patients (Gustave-Roussy Institute) and a validation cohort of 54 patients (Cochin Hospital).
O
Outcome
Specific survival after discovery of the first metastasishard clinical

In patients with metastatic adrenocortical carcinoma, the number of tumoral organs and the primary tumor's mitotic rate are key prognostic factors for survival.

Cite This Study

Assié et al. (2006) studied this question.

synapsesocial.com/papers/6a73f64fc06fdc6c46a8c0c8https://doi.org/10.1210/jc.2006-0706
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Adrenocortical Carcinoma: Clinical Update2006 · 778 citations
  2. 2Adrenocortical carcinoma2001 · 160 citations
  3. 3Adrenal cortical carcinoma in Norway, 1970–19841992 · 101 citations
  4. 4Comparative histologic study of 43 metastasizing and nonmetastasizing adrenocortical tumors1984 · 929 citations
  5. 5Morphologic characteristics of benign and malignant adrenocortical tumors1985 · 330 citations