TIM-1 defines a human regulatory B cell population that is altered in frequency and function in systemic sclerosis patients

This is the authors' abstract. We don't add key points for this paper.

TIM-1 is a unique marker for the identification of a human IL-10⁺ Breg subpopulation which is partially superimposed with transitional B cells. Alterations in TIM-1⁺ B cells could contribute to the development of autoimmune diseases such as SSc.