Investigational study indicates IL-17 and S100A7 involvement in vulvar lichen sclerosus, suggesting targeted therapy using IL-17 inhibitors could be effective.
The results of our study may suggest the involvement of IL-17 and S100A7 in the pathogenesis of VLS. The better understanding of this disease may lead to the development of novel, effective therapeutic strategies e.g. using well-known biologics IL-17 inhibitors class.
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Baran et al. (2024) studied this question.
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