Why the study?
Do predictors of fluid responsiveness reliably predict the response of cardiac output to volume expansion in adult critically ill patients mechanically ventilated at low tidal volumes?
Population
Adult patients mechanically ventilated at tidal volumes ≤ 8 ml kg-1
Design
Systematic review and meta-analysis
Authors
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Supports cautious use of fluid responsiveness predictors during low-tidal-volume ventilation; confirms reliability while highlighting technical and clinical performance modifiers.
Do predictors of fluid responsiveness reliably predict the response of cardiac output to volume expansion in adult critically ill patients mechanically ventilated at low tidal volumes?
Predictors of fluid responsiveness are generally reliable in critically ill adults ventilated at low tidal volumes, though their performance is affected by technical and clinical variables.
Sánchez et al. (2021) studied this question.