What question did this study set out to answer?

To evaluate the risk of hematological malignancies associated with low-dose ionizing radiation exposure from CT examinations performed in childhood, adolescence, and young adulthood.

November 9, 2023Nature MedicineOpen Access

Risk of hematological malignancies from CT radiation exposure in children, adolescents and young adults

View Full Paper

Ask AI

Bookmark

Authors

MGMagda Bosch de Basea GómezTeulades i Façanes Multifuncionals (Spain)ITIsabelle Thierry-ChefInstitut de Radioprotection et de Sûreté Nucléaire RHRichard HarbronWorld Health Organization - Pakistan

Discussion

Member takes

Implication

Multinational cohort study finds increased hematological cancer risk from CT scans in young people, highlighting the need for scan justification and dose optimization.

Key Points

To evaluate the risk of hematological malignancies associated with low-dose ionizing radiation exposure from CT examinations performed in childhood, adolescence, and young adulthood.
Followed a multinational cohort (EPI-CT) of 948,174 individuals who underwent CT examinations before age 22 across nine European countries.
Estimated radiation doses to active bone marrow using scanned anatomical regions, patient characteristics, time periods, and inferred CT technical parameters.
Identified 790 hematological malignancy cases, showing an association with cumulative bone marrow dose with an excess relative risk of 1.96 (95% CI 1.10 to 3.12) per 100 mGy.
Observed similar risk estimates for lymphoid and myeloid malignancies, projecting that 1 to 2 individuals per 10,000 scanned at an average dose of 8 mGy will develop an attributable hematological malignancy within 12 years.

Cite This Study

Gómez et al. (2023) studied this question.

synapsesocial.com/papers/69d77d94ef4aa71f97f3176f https://doi.org/10.1038/s41591-023-02620-0

View Full Paper

Ask AI

Bookmark

Implication

Multinational cohort study finds increased hematological cancer risk from CT scans in young people, highlighting the need for scan justification and dose optimization.

Risk of hematological malignancies from CT radiation exposure in children, adolescents and young adults

Discussion

Member takes

Implication

Key Points

Cite This Study

Risk of hematological malignancies from CT radiation exposure in children, adolescents and young adults

Discussion

Member takes

Implication

Key Points

Cite This Study

Also Consider

Also Consider