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February 13, 2021SHILAP Revista de lepidopterología125 citationsOpen Access

Prognostic Significance of CD4+ and CD8+ Tumor-Infiltrating Lymphocytes in Head and Neck Squamous Cell Carcinoma: A Meta-Analysis

DBDaniele BorsettoMTMichele TomasoniKPKarl Payne

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Abstract

The findings from this meta-analysis demonstrate the prognostic significance of CD8+ and CD4+ TILs in HNSCC and variation in tumor subsite warrants further focused investigation. We highlight how TILs may serve as predictive biomarkers to risk stratify patients into treatment groups, with applications in immune-checkpoint inhibitors notable areas for further research.

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Borsetto et al. (2021) studied this question.

synapsesocial.com/papers/69d77df6db9d5e1bf4b8b1c7https://doi.org/10.3390/cancers13040781
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