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November 1, 1984American Journal of Psychiatry

A new rating scale for Alzheimer's disease

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Authors

WRWilma G. RosenAlbert Einstein College of MedicineRMRichard C. MohsAgeneBio (United States)KDKenneth L. DavisUniversity of North Carolina at Charlotte

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Implication

Randomized trial develops a new rating scale to assess severity of cognitive dysfunction in Alzheimer's patients, indicating improved evaluation methods.

Key Points

  • This research aims to create a rating scale for assessing cognitive and noncognitive dysfunctions in Alzheimer's disease.
  • Developed the Alzheimer's Disease Assessment Scale for evaluation
  • Rated 27 subjects with Alzheimer's disease and 28 normal elderly subjects on 40 items
  • Utilized intraclass and Spearman rank-order correlation coefficients for reliability assessment.
  • Identified 21 items with intraclass correlation coefficients ranging from .650 to .989
  • Demonstrated significant Spearman rank-order correlation coefficients for test-retest reliability (range, .514-1)
  • Subjects with Alzheimer's exhibited greater cognitive and noncognitive dysfunction compared to normal elderly subjects.

Cite This Study

Rosen et al. (1984) studied this question.

synapsesocial.com/papers/69d787dbb1cb92dd1bb8b8aehttps://doi.org/10.1176/ajp.141.11.1356
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Association Between Quantitative Measures of Dementia and of Senile Change in the Cerebral Grey Matter of Elderly Subjects1968 · 4,144 citations
  2. 2RELIABILITY AND VALIDITY OF A SCALE FOR ASSESSING THE FUNCTIONING OF GERIATRIC PATIENTS1970 · 114 citations
  3. 3Physical and Mental Impairment-of-Function Evaluation in the Aged: The PAMIE Scale1972 · 61 citations
  4. 4ALZHEIMERʼS DISEASE1962 · 113 citations