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April 1, 2000Journal of Biological ChemistryOpen Access

Farnesoid X Receptor Responds to Bile Acids and Represses Cholesterol 7α-Hydroxylase Gene (CYP7A1) Transcription

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Authors

JCJohn Y.L. ChiangNortheast Ohio Medical UniversityRKRhonda KimmelCenter for Global HealthCWCary WeinbergerNational Institute of Environmental Health Sciences

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Cite This Study

Chiang et al. (2000) studied this question.

synapsesocial.com/papers/69d78a54db9d5e1bf4b8b526https://doi.org/10.1074/jbc.275.15.10918
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Phytol metabolites are circulating dietary factors that activate the nuclear receptor RXR.1996 · 202 citations
  2. 2Peroxisome proliferator-activated receptor α (PPARα) and agonist inhibit cholesterol 7α-hydroxylase gene (CYP7A1) transcription2000 · 184 citations
  3. 3Identification of a Nuclear Receptor for Bile Acids1999 · 2,732 citations
  4. 4Orphan Receptors Chicken Ovalbumin Upstream Promoter Transcription Factor II (COUP-TFII) and Retinoid X Receptor (RXR) Activate and Bind the Rat Cholesterol 7α-Hydroxylase Gene (CYP7A)1997 · 55 citations