March 9, 1999Circulation551 citations
View Full PaperSelective Potentiation of Peripheral Chemoreflex Sensitivity in Obstructive Sleep Apnea
Structured PICO
Is Obstructive Sleep Apnea associated with altered autonomic, hemodynamic, and ventilatory responses to peripheral chemoreceptor activation by hypoxia?
P
Population
Patients with Obstructive Sleep Apnea (OSA)
I
Intervention
Peripheral chemoreceptor activation by hypoxia
O
Outcome
Autonomic, hemodynamic, and ventilatory responsessurrogate
OSA selectively potentiates physiological responses to hypoxia, highlighting a potential mechanism for cardiovascular risk in these patients.
Abstract
OSA is associated with a selective potentiation of autonomic, hemodynamic, and ventilatory responses to peripheral chemoreceptor activation by hypoxia.