Why the study?
Does peri-operative gastric protection with ranitidine prevent gastrointestinal bleeding in patients receiving aspirin thromboprophylaxis for hip and knee arthroplasty?
Does peri-operative gastric protection with ranitidine prevent gastrointestinal bleeding in patients receiving aspirin thromboprophylaxis for hip and knee arthroplasty?
The authors recommend ranitidine for gastric protection to prevent gastrointestinal bleeding in patients receiving aspirin thromboprophylaxis after hip or knee arthroplasty.
May warrant ranitidine for GI protection with aspirin thromboprophylaxis in arthroplasty; leaves open need for randomized confirmation.
Based on this experience, we recommend the use of peri-operative gastric protection with ranitidine when aspirin is used for thromboprophylaxis in hip and knee arthroplasty.
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Madhusudhan et al. (2008) studied this question.
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