Population
Several typical cell lines
Design
Preclinical
Authors
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Enables tunable co-expression ratios in preclinical vectors; leaves open translation to recombinant production or therapeutic applications.
Alternative-splicing-based bicistronic vectors allow for efficient and reproducible modulation of the ratio between co-expressed proteins, which is useful for basic science and recombinant antibody production.
Fallot et al. (2009) studied this question.
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