April 7, 2015Open Access

TGF-β1-Mediated Differentiation of Fibroblasts Is Associated with Increased Mitochondrial Content and Cellular Respiration

Structured PICO

Does TGF-β1 alter mitochondrial content and cellular respiration during the differentiation of fibroblasts?

Population

fibroblasts

Intervention

TGF-β1

Outcome

differentiation of fibroblasts, energetic remodeling, mitochondrial respiration, and mitochondrial contentsurrogate

TGF-β1-mediated fibroblast differentiation involves energetic remodeling characterized by increased mitochondrial content and respiration.

Abstract

TGF-β1 induced differentiation of fibroblasts is accompanied by energetic remodeling of myofibroblasts with an increase in mitochondrial respiration and mitochondrial content.

AI에게 질문

Bookmark

View Full Paper

Cite This Study

Negmadjanov et al. (Tue,) studied this question.

synapsesocial.com/papers/69d7b6f71f14cb2b27b8a81f https://doi.org/https://doi.org/10.1371/journal.pone.0123046

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

AI에게 질문

Bookmark

View Full Paper