Polygenic Risk Score, Parental Socioeconomic Status, Family History of Psychiatric Disorders, and the Risk for Schizophrenia

Esben Agerbo; Patrick F. Sullivan; Bjarni J. Vilhjálmsson; Carsten Bøcker Pedersen; Ole Mors; Anders D. Børglum; David M. Hougaard; Mads V. Hollegaard; Sandra Meier; Manuel Mattheisen; Stephan Ripke; Naomi R. Wray; Preben Bo Mortensen

doi:10.1001/jamapsychiatry.2015.0346

April 2, 2015JAMA PsychiatryOpen Access

Polygenic Risk Score, Parental Socioeconomic Status, Family History of Psychiatric Disorders, and the Risk for Schizophrenia

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Abstract

Schizophrenia was associated with the polygenic risk score, family psychiatric history, and socioeconomic status. Our study demonstrated that family history of schizophrenia/psychoses is partly mediated through the individual's genetic liability.

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Agerbo et al. (2015) studied this question.

synapsesocial.com/papers/69d7c410f39344339dd1805a https://doi.org/10.1001/jamapsychiatry.2015.0346

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Polygenic Risk Score, Parental Socioeconomic Status, Family History of Psychiatric Disorders, and the Risk for Schizophrenia

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Abstract

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Polygenic Risk Score, Parental Socioeconomic Status, Family History of Psychiatric Disorders, and the Risk for Schizophrenia

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Abstract

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