Comparison of seven surrogate insulin resistance indexes for prediction of incident coronary heart disease risk: a 10-year prospective cohort study

Figure 1. Flow diagram of patient selection. CVD, Cardiovascular disease.

Figure 2. Kaplan-Meier curves of CHD by IR surrogates quintiles. The cumulative incidence of CHD during follow-up grouped according to the IR surrogates quintiles was analyzed by Kaplan-Meier curves, including CVAI (A), VAI (B), LAP (C), TyG (D), TyG-BMI (E), TyG-WC (F), TyG-WHtR (G). The p value was calculated with the log-rank test. CHD, coronary heart disease; IR, insulin resistance; CVAI, Chinese visceral adiposity index; VAI, visceral adiposity index; LAP, lipid accumulation product; TyG, triglyceride glucose; BMI, body mass index; WC, waist circumference; WHtR, waist-to-height ratio.

Figure 3. Receiver operating characteristic curves of CHD by IR surrogates quintiles. The AUCs (95%CI) of indexes are as follows: CVAI: 0.632(0.597,0.667); VAI: 0.560(0.522,0.598); LAP:0.593(0.557,0.629); TyG: 0.595(0.560,0.630); TyG-BMI: 0.609(0.574,0.644); TyG-WC: 0.606(0571,0.641); TyG-WHtR: 0.609(0.574,0.645), respectively, p<0.01. CHD, coronary heart disease; IR, insulin resistance; CVAI, Chinese visceral adiposity index; VAI, visceral adiposity index; LAP, lipid accumulation product; TyG, triglyceride glucose; BMI, body mass index; WC, waist circumference; WHtR, waist-to-height ratio.