October 22, 2020Open Access

Liquid Biopsy for Invasive Mold Infections in Hematopoietic Cell Transplant Recipients With Pneumonia Through Next-Generation Sequencing of Microbial Cell-Free DNA in Plasma

JHJoshua A. HillFred Hutch Cancer Center SDSudeb C. DalaiBoston University DHDavid K. HongSpero Therapeutics (United States)

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Abstract

Noninvasive mcfDNA-Seq had moderate sensitivity and high specificity, NPV, and PPV for pulmonary IMI after HCT, particularly for non-Aspergillus species.

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