June 23, 2018Cellular and Molecular Life SciencesOpen Access

Molecular mechanisms of hepatic lipid accumulation in non-alcoholic fatty liver disease

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Population

Patients with non-alcoholic fatty liver disease (NAFLD)

Design

Review

Authors

DIDavid Højland IpsenNovo Nordisk (Denmark)JLJens LykkesfeldtUniversity of Copenhagen PTPernille Tveden‐NyborgUniversity of Copenhagen

Discussion

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Implication

Clarifies lipid imbalance driving NAFLD steatosis; leaves open targeted interventions pending prospective validation.

Structured PICO

Population

Patients with non-alcoholic fatty liver disease (NAFLD)

This review highlights the molecular imbalance between lipid acquisition and disposal in NAFLD, which drives hepatic steatosis and contributes to systemic metabolic diseases.

Cite This Study

Ipsen et al. (2018) studied this question.

synapsesocial.com/papers/69d7ca4233ca018b39ae2d4f https://doi.org/10.1007/s00018-018-2860-6

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Molecular mechanisms of hepatic lipid accumulation in non-alcoholic fatty liver disease

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Molecular mechanisms of hepatic lipid accumulation in non-alcoholic fatty liver disease

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider