What question did this study set out to answer?

To evaluate the diagnostic accuracy of the Xpert MTB/RIF Ultra assay for detecting Mycobacterium tuberculosis and determining rifampicin resistance.

November 30, 2017ViewOpen Access

Xpert MTB/RIF Ultra for detection of Mycobacterium tuberculosis and rifampicin resistance: a prospective multicentre diagnostic accuracy study

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Authors

SDSusan E. DormanMedical University of South Carolina SSSamuel G. SchumacherFoundation for Innovative New Diagnostics DADavid AllandRutgers, The State University of New Jersey

Discussion

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Implication

Prospective multicentre study demonstrates diagnostic accuracy of Xpert MTB/RIF Ultra, highlighting improved detection of tuberculosis and rifampicin resistance.

Key Points

To evaluate the diagnostic accuracy of the Xpert MTB/RIF Ultra assay for detecting Mycobacterium tuberculosis and determining rifampicin resistance.
Conducted a prospective, multicentre diagnostic accuracy study across multiple clinical evaluation centers.
Assessed performance of the Xpert MTB/RIF Ultra assay against microbiological reference standards.
Quantified diagnostic sensitivity and specificity for the detection of Mycobacterium tuberculosis.
Determined diagnostic accuracy benchmarks for identifying rifampicin-resistant tuberculosis strains.

Cite This Study

Dorman et al. (2017) studied this question.

synapsesocial.com/papers/69d7d878319e71454dbedbbf https://doi.org/10.1016/s1473-3099(17)30691-6

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Implication

Prospective multicentre study demonstrates diagnostic accuracy of Xpert MTB/RIF Ultra, highlighting improved detection of tuberculosis and rifampicin resistance.

Xpert MTB/RIF Ultra for detection of Mycobacterium tuberculosis and rifampicin resistance: a prospective multicentre diagnostic accuracy study

Discussion

Member takes

Implication

Key Points

Cite This Study

Xpert MTB/RIF Ultra for detection of Mycobacterium tuberculosis and rifampicin resistance: a prospective multicentre diagnostic accuracy study

Discussion

Member takes

Implication

Key Points

Cite This Study

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