Why the study?
Does genetically elevated non-fasting triglycerides and calculated remnant cholesterol increase the risk of myocardial infarction?
Does genetically elevated non-fasting triglycerides and calculated remnant cholesterol increase the risk of myocardial infarction?
Genetically elevated remnant cholesterol in hypertriglyceridemia is causally associated with an increased risk of myocardial infarction.
Potential MI risk marker in hypertriglyceridaemia; extends genetic evidence but should not yet change practice.
These data are consistent with a causal association between elevated levels of remnant cholesterol in hypertriglyceridaemia and an increased risk of MI. Limitations include that remnants were not measured directly, and that APOA5 genetic variants may influence other lipoprotein parameters.
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Jørgensen et al. (2012) studied this question.
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