Why the study?
Does plasma lipid profiling identify specific lipid species associated with prediabetes and type 2 diabetes?
Population
351 participants from the Australian Diabetes, Obesity and Lifestyle Study including 117 with type 2…
Comparison
Lipidomic analysis measuring 259 individual… vs Normal glucose tolerant participants
Design
Cohort
Authors
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Prediabetes shows diabetes-associated plasma lipid changes; hypothesis-generating for early profiling but leaves clinical utility open.
Does plasma lipid profiling identify specific lipid species associated with prediabetes and type 2 diabetes?
The aberration of the plasma lipidome associated with type 2 diabetes is clearly present in prediabetes, prior to the onset of type 2 diabetes.
Meikle et al. (2013) studied this question.
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