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June 10, 2015Journal of Biological ChemistryOpen Access

The Role of Phosphodiesterase 12 (PDE12) as a Negative Regulator of the Innate Immune Response and the Discovery of Antiviral Inhibitors

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Authors

EWEdgar R. WoodTarget (United States)RBRandy K. BledsoeCellular Research (United States)JCJing ChaiChengdu University of Information Technology

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Wood et al. (2015) studied this question.

synapsesocial.com/papers/69d7ef985c3030ff03d186a2https://doi.org/10.1074/jbc.m115.653113
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Also Consider

Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Viral Phosphodiesterases That Antagonize Double-Stranded RNA Signaling to RNase L by Degrading 2-5A2014 · 73 citations
  2. 2Homologous 2′,5′-phosphodiesterases from disparate RNA viruses antagonize antiviral innate immunity2013 · 128 citations