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October 31, 2017Civil War Book ReviewOpen Access

A communal catalogue reveals Earth’s multiscale microbial diversity

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Authors

LTLuke ThompsonJSJon G. SandersDMDaniel McDonald

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Overview

Meta-analysis reveals multiscale patterns of bacterial and archaeal diversity across global environments, highlighting a standardized reference framework for future microbiome research.

Key Points

  • To establish a standardized analytical framework and global reference database for tracking and comparing bacterial and archaeal diversity across varied environments.
  • Conducted a large-scale meta-analysis of microbial community samples gathered across multiple global ecosystems by the Earth Microbiome Project.
  • Standardized sampling and sequencing protocols across collaborating laboratories.
  • Analyzed bacterial and archaeal ribosomal RNA gene sequences utilizing exact sequence variants rather than clustered operational taxonomic units.
  • Produced a comprehensive reference database that successfully contextualizes DNA sequence data across diverse ecosystems on an unprecedented scale.
  • Established an extensible analytical framework that enables integration of future sequencing datasets into a unified model of global microbial diversity.

Cite This Study

Thompson et al. (2017) studied this question.

synapsesocial.com/papers/69d7efe73eff0c9dfaae2ae9https://doi.org/10.1038/nature24621
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