Depression and severe pain are highly comorbid in low- and middle-income countries, independent of other chronic conditions.
Supports integrated depression-pain screening in LMICs; confirms independence from anxiety and comorbidities in global data.
Depression and severe pain are highly comorbid across LMICs, independent of anxiety and chronic medical conditions. Whether depression treatment or pain management in patients with comorbid pain and depression leads to better clinical outcome is an area for future research.
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Stubbs et al. (2017) studied this question.
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