Why the study?
Does general anesthesia cause long-term neurodevelopmental deficits in children?
Does general anesthesia cause long-term neurodevelopmental deficits in children?
Current evidence suggests limiting the duration, frequency, and dose of general anesthesia in children to mitigate potential long-term neurodevelopmental deficits.
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May warrant limiting pediatric anesthesia exposure; extends suggestive evidence while leaving causal confirmation open.
Based on current studies, it is necessary to endeavor to limit the duration and numbers of anesthesia and the dose of anesthetic agents. For future studies, we require cohort studies with rich sources of data and appropriate outcome measures, and carefully designed and adequately powered clinical trials testing plausible interventions in relevant patient populations.
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Xiao et al. (2022) studied this question.
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