Why the study?
Does perioperative anesthetic exposure and brain injury affect 12-month neurodevelopmental outcomes in neonates undergoing cardiac surgery?
Population
Neonates with congenital heart disease (CHD) undergoing cardiac surgery
Design
Cohort
Follow-up
12 months
Authors
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Does not support practice change in neonatal cardiac surgery; hypothesis-generating for prospective trials on VAA exposure and neurodevelopment.
Does perioperative anesthetic exposure and brain injury affect 12-month neurodevelopmental outcomes in neonates undergoing cardiac surgery?
Perioperative factors including volatile anesthetic exposure and brain injury are associated with worse 12-month neurodevelopmental outcomes in neonates after cardiac surgery.
Andropoulos et al. (2014) studied this question.
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