Key result
Multifaceted management targets interdependent heart failure and arrhythmias in adult congenital heart disease.
Why the study?
Heart failure and arrhythmias are interdependent major causes of morbidity and mortality in adults with congenital heart disease that require multifaceted management approaches.
This review highlights the interdependent nature of arrhythmias and heart failure in adults with congenital heart disease, emphasizing the need for a multifaceted management approach combining pharmacotherapy, hemodynamic optimization, and device or catheter ablation therapy.
Answers are grounded in this paper and cite their sources.
Hypothesis-generating for arrhythmias in ACHD-HF; prospective trials needed before clinical adoption.
Heart failure and arrhythmias represent 2 major causes of mortality and morbidity in adults with congenital heart disease. Arrhythmias and heart failure are interdependent, and one may exacerbate the other. Treatment of one also has a positive impact on the other. Management approaches need to be multifaceted, including pharmacotherapy, optimization of hemodynamic status with catheter-based or surgical interventions, and specific management of arrhythmia with device or catheter ablation therapy.
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Dodeja et al. (2026) conducted a review in Adult congenital heart disease with heart failure and arrhythmias. Multifaceted management (pharmacotherapy, catheter-based or surgical hemodynamic optimization, device therapy, or catheter ablation) was evaluated. Multifaceted management combining pharmacotherapy, hemodynamic optimization, and device or catheter ablation addresses interdependent heart failure and arrhythmias in adults with congenital heart disease.
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