Evaluating the risks and benefits of continuing versus withholding renin–angiotensin system inhibitors: a systematic review and meta-analysis with trial sequential analysis

Figures

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  Fig 1. PRISMA flow chart of the screening process. WOS, Web of Science.

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  Fig 2. (a) Forest plot of cardiovascular complications; (b) leave-one-out sensitivity analysis of cardiovascular complications; (c) a trial sequential analysis of cardiovascular complications.

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  Fig 3. a) Forest plot of acute kidney injury; (b) leave-one-out sensitivity analysis of acute kidney injury; (c) a trial sequential analysis of acute kidney injury.

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  Fig 4. (a) Forest plot of all-cause mortality; (b) forest plot of intraoperative hypotension; (c) leave-one-out sensitivity analysis of intraoperative hypotension.

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  Fig 5. (a) Forest plot of postoperative hypertension; (b) forest plot of postoperative severe hypertension; (c) quality assessment of risk of bias for the included trials.