May 26, 2010Investigative Ophthalmology & Visual ScienceOpen Access

Mitochondrial DNA Damage as a Potential Mechanism for Age-Related Macular Degeneration

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PKPabalu P. KarunadharmaThe Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology CNCurtis L. NordgaardUniversity of Minnesota Medical Center TOTimothy W. OlsenMayo Clinic

Abstract

Collectively, the data indicate that mtDNA is preferentially damaged with AMD progression. These results suggest a potential link between mt dysfunction due to increased mtDNA lesions and AMD.

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Cite This Study

Karunadharma et al. (2010) studied this question.

synapsesocial.com/papers/69d80bd0617ce96c42ae29b6 https://doi.org/10.1167/iovs.10-5429

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Abstract

Collectively, the data indicate that mtDNA is preferentially damaged with AMD progression. These results suggest a potential link between mt dysfunction due to increased mtDNA lesions and AMD.

Mitochondrial DNA Damage as a Potential Mechanism for Age-Related Macular Degeneration

Abstract

Discussion

Cite This Study

Mitochondrial DNA Damage as a Potential Mechanism for Age-Related Macular Degeneration

Abstract

Discussion

Cite This Study

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