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January 1, 2025The journal of nutrition health & agingOpen Access

Global consensus on optimal exercise recommendations for enhancing healthy longevity in older adults (ICFSR)

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Authors

MIMíkel IzquierdoPreventive CardiologyPBPhilipe de Souto BarretoUniversité Toulouse III - Paul SabatierHAHidenori AraiGeneral / Preventive / Lipids

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Implication

Consensus statement outlines evidence-based exercise regimens for healthy longevity in older adults, highlighting the necessity of prescribing physical activity alongside pharmacotherapy.

Key Points

  • To establish an international clinical consensus on evidence-based exercise prescriptions and physical activity recommendations designed to slow biological aging, treat geriatric syndromes, and extend healthspan.
  • Synthesized findings from randomized controlled trials examining aerobic, progressive resistance, balance, and multicomponent exercise interventions in older adults.
  • Formulated evidence-based clinical guidance addressing biological aging phenotypes, non-communicable chronic diseases, frailty, sarcopenia, and functional dependence across outpatient and residential care settings.
  • Progressive resistance training and multicomponent programs incorporating cognitive tasks significantly alleviate the hallmarks of frailty, reverse sarcopenia, improve balance and mobility, and reduce fall incidence.
  • Tailored exercise elicits potent dose-response physiological adaptations that slow biological aging, serving as both disease prevention and targeted adjunctive therapy to reduce polypharmacy and inappropriate drug prescriptions.
  • Optimizing clinical benefits requires individualized exercise dosing and widespread educational training for geriatricians and healthcare providers to embed exercise prescriptions directly into standard medical care.

Cite This Study

Izquierdo et al. (2025) studied this question.

synapsesocial.com/papers/69d80c2cf39344339dd19152https://doi.org/10.1016/j.jnha.2024.100401
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