Transcriptomic analysis reveals shared epithelial responses and molecular heterogeneity in acute kidney injury, suggesting paths for personalized therapies.
The study provides an extensive resource of the cell type-specific transcriptomic responses associated with critical illness-associated AKI in humans, highlighting recurrent disease-associated signatures and inter-individual heterogeneity. Personalized molecular disease assessment in human AKI may foster the development of tailored therapies.
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Hinze et al. (2022) studied this question.
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