The study provides evidence for the co-existence of multiple PKoV strains in single pigs and possible recombination events, suggesting PKoV as a likely causative agent of high-mortality diarrhea in China since 2010.
Supports expanded PKoV surveillance in asymptomatic pigs; leaves open recombination's contribution to virulence in Chinese outbreaks.
PKoV was endemic in Sichuan Province regardless of whether pigs were healthy or suffering from diarrhea. Based on our statistical analyses, we suggest that PKoV was the likely causative agent of high-mortality diarrhea in China from 2010. For the first time, we provide evidence for the co-existence of multiple PKoV strains in one pig, and possible recombination events in the VP1 region. Our findings provide further insights into the molecular properties of PKoV, along with its epidemiology.
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Chen et al. (2013) studied this question.
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