Key result
Capsid gene sequencing reveals Aichi virus strains cluster into two distinct lineages by geographic origin.
Why the study?
A classification of Aichi viruses based on the capsid gene was needed to understand their phylogenetic relationships across different countries.
Sequence analysis of the capsid gene of Aichi viruses suggests a classification into two distinct lineages based on geographic origin.
Geographic clustering of Aichi virus lineages may guide regional surveillance; leaves open clinical or evolutionary implications.
Sequence analysis of the capsid gene of Aichi viruses was performed on 12 strains detected in Japan, Bangladesh, Thailand, and Vietnam during 2002-2005. The phylogenetic tree constructed from 17 nucleotide sequences of the capsid gene of the strains studied and reference strains demonstrated that Aichi virus strains clustered into two branches. A classification of Aichi viruses based on the capsid gene was proposed, in which lineage I consists of the Aichi virus strains detected from Japan, Thailand, Vietnam, and Germany, and lineage II includes Bangladeshi strains and a Brazilian strain.
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Pham et al. (2008) studied Aichi virus (n=17). Sequence analysis of the capsid gene was evaluated on Phylogenetic classification. Sequence analysis of the capsid gene demonstrated that Aichi virus strains cluster into two distinct lineages based on geographic origin.
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