What question did this study set out to answer?

To evaluate the diagnostic accuracy of HPV testing on self-collected urine and vaginal samples compared to physician-collected cervical swabs in women referred for colposcopy.

September 7, 2023SHILAP Revista de lepidopterologíaOpen Access

Accuracy of Human Papillomavirus (HPV) Testing on Urine and Vaginal Self-Samples Compared to Clinician-Collected Cervical Sample in Women Referred to Colposcopy

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Authors

MMMarianna MartinelliUniversity of Milano-Bicocca CGChiara GiubbiAlessandro Manzoni Hospital MMMaria Letizia Di MeoAzienda Ospedaliera San Gerardo

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Implication

Cohort study reveals high concordance between self-collected urine or vaginal tests and clinician swabs in women with abnormal cytology, highlighting opportunities to expand cervical cancer screening.

Key Points

To evaluate the diagnostic accuracy of HPV testing on self-collected urine and vaginal samples compared to physician-collected cervical swabs in women referred for colposcopy.
Enrolled a cohort of 245 women presenting with abnormal cervical cytology who were referred for colposcopy.
Obtained self-collected vaginal swabs, self-collected urine specimens, and physician-collected cervical swabs, testing all samples using the Anyplex™II HPV28 assay.
HPV positivity rates were 75.1% for clinician-collected cervical swabs, 78.4% for vaginal self-samples, and 77.1% for urine self-samples.
High-risk HPV concordance between self-collected specimens and clinician-collected cervical samples was strong, demonstrating a Cohen's kappa of k = 0.898 for vaginal swabs and k = 0.715 for urine samples.

Cite This Study

Martinelli et al. (2023) studied this question.

synapsesocial.com/papers/69d811c2ec670a5632d17e23 https://doi.org/10.3390/v15091889

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Accuracy of Human Papillomavirus (HPV) Testing on Urine and Vaginal Self-Samples Compared to Clinician-Collected Cervical Sample in Women Referred to Colposcopy

Discussion

Member takes

Implication

Key Points

Cite This Study

Accuracy of Human Papillomavirus (HPV) Testing on Urine and Vaginal Self-Samples Compared to Clinician-Collected Cervical Sample in Women Referred to Colposcopy

Discussion

Member takes

Implication

Key Points

Cite This Study

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