Development of a concise, scalable synthesis of a CCR1 antagonist utilizing a continuous flow Curtius rearrangement

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1. 1Ueber die Verbindungen der Cyanursäure und Cyansäure mit Aethyloxyd, Methyloxyd, Amyloxyd und die daraus entstehenden Producte; Acetyl‐ und Metacetylharnstoff, Methylamin, Aethylamin, Valeramin1849 · 33 citations
2. 2The Atom Economy—A Search for Synthetic Efficiency1991 · 4,752 citations
3. 3CCL9/MIP‐1γ and its receptor CCR1 are the major chemokine ligand/receptor species expressed by osteoclasts2002 · 152 citations
4. 4Rheumatoid arthritis2010 · 3,018 citations
5. 5Rheumatoid arthritis2014 · 7 citations