Why the study?
Does the APOE4 polymorphism predispose to longer duration of delirium in critically ill patients?
Does the APOE4 polymorphism predispose to longer duration of delirium in critically ill patients?
The APOE4 allele is identified as a genetic predisposition for prolonged delirium in critically ill patients.
APOE4 may flag higher delirium risk in critical illness; hypothesis-generating and requires prospective validation before clinical use.
APOE4 allele represents the first demonstrated genetic predisposition to longer duration of delirium in humans.
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Ely et al. (2006) studied this question.
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