What question did this study set out to answer?

To externally validate the predictive performance, discrimination, and calibration of a widely implemented proprietary sepsis prediction model in hospitalized patients.

June 21, 2021JAMA Internal MedicineOpen Access

External Validation of a Widely Implemented Proprietary Sepsis Prediction Model in Hospitalized Patients

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To externally validate the predictive performance, discrimination, and calibration of a widely implemented proprietary sepsis prediction model in hospitalized patients.
Conducted an external validation cohort study assessing the performance of the Epic Sepsis Model (ESM) among hospitalized patients.
The proprietary model demonstrated poor discrimination and calibration for predicting the onset of sepsis in the external validation cohort.
Widespread implementation of the model despite poor predictive capability identifies potential vulnerabilities in hospital-level and national sepsis management strategies.

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Implication

Cohort study reveals poor discrimination and calibration of a proprietary sepsis model in hospitalized patients, highlighting major concerns for national sepsis management.

Cite This Study

Wong et al. (2021) studied this question.

synapsesocial.com/papers/69d815a73eff0c9dfaae3465 https://doi.org/10.1001/jamainternmed.2021.2626

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Implication

Cohort study reveals poor discrimination and calibration of a proprietary sepsis model in hospitalized patients, highlighting major concerns for national sepsis management.

External Validation of a Widely Implemented Proprietary Sepsis Prediction Model in Hospitalized Patients

Key Points

Discussion

Implication

Cite This Study

External Validation of a Widely Implemented Proprietary Sepsis Prediction Model in Hospitalized Patients

Key Points

Discussion

Implication

Cite This Study

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