What question did this study set out to answer?

To review and analyze CMOS electrochemical instrumentation circuits, their design trade-offs, and recent integration trends for miniaturized biosensor microsystems.

December 31, 2016SensorsOpen Access

CMOS Electrochemical Instrumentation for Biosensor Microsystems: A Review

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Authors

HLHaitao Li XLXiaowen Liu LLLin Li

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Overview

Literature review outlines circuit topologies for CMOS electrochemical instrumentation, highlighting design trade-offs to advance miniaturized point-of-care microsystems.

Key Points

To review and analyze CMOS electrochemical instrumentation circuits, their design trade-offs, and recent integration trends for miniaturized biosensor microsystems.
Categorized reported CMOS electrochemical instrumentation circuits into functional classes based on circuit architecture and sensing principles.
Evaluated performance trade-offs across reported circuits and reviewed technical challenges associated with on-CMOS sensor integration.
CMOS-based instrumentation circuits provide substantial reductions in form factor, response time, and manufacturing cost compared to conventional benchtop instruments.
Circuit architectures exhibit critical design trade-offs among dynamic range, noise performance, silicon area, and power consumption across different electrochemical modalities.
Monolithic on-CMOS integration remains constrained by material compatibility and microfabrication complexity required to interface biological layers directly with silicon.

Cite This Study

Li et al. (2016) studied this question.

synapsesocial.com/papers/69d8161a7392c8ce61bee80d https://doi.org/10.3390/s17010074

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December 31, 2016SensorsOpen Access

CMOS Electrochemical Instrumentation for Biosensor Microsystems: A Review

View Full Paper

Ask AI

Bookmark

Authors

HLHaitao Li XLXiaowen Liu LLLin Li

Discussion

Member takes

Overview

Literature review outlines circuit topologies for CMOS electrochemical instrumentation, highlighting design trade-offs to advance miniaturized point-of-care microsystems.

Key Points

To review and analyze CMOS electrochemical instrumentation circuits, their design trade-offs, and recent integration trends for miniaturized biosensor microsystems.
Categorized reported CMOS electrochemical instrumentation circuits into functional classes based on circuit architecture and sensing principles.
Evaluated performance trade-offs across reported circuits and reviewed technical challenges associated with on-CMOS sensor integration.
CMOS-based instrumentation circuits provide substantial reductions in form factor, response time, and manufacturing cost compared to conventional benchtop instruments.
Circuit architectures exhibit critical design trade-offs among dynamic range, noise performance, silicon area, and power consumption across different electrochemical modalities.
Monolithic on-CMOS integration remains constrained by material compatibility and microfabrication complexity required to interface biological layers directly with silicon.

Cite This Study

Li et al. (2016) studied this question.

synapsesocial.com/papers/69d8161a7392c8ce61bee80d https://doi.org/10.3390/s17010074

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