What question did this study set out to answer?

Assess the efficacy and safety of a cannabidiol-rich botanical extract for the symptomatic management of ulcerative colitis.

March 10, 2018Inflammatory Bowel Diseases

A Randomized, Double-blind, Placebo-controlled, Parallel-group, Pilot Study of Cannabidiol-rich Botanical Extract in the Symptomatic Treatment of Ulcerative Colitis

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Authors

PIPeter M. IrvingGuy's and St Thomas' NHS Foundation Trust TITariq IqbalUniversity Hospitals Birmingham NHS Foundation Trust CNChuka NwokoloUniversity College Hospital

Discussion

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Implication

Randomized double-blind trial finds potential symptomatic benefit from cannabidiol extract in ulcerative colitis, suggesting therapeutic value despite an unmet primary endpoint.

Key Points

Assess the efficacy and safety of a cannabidiol-rich botanical extract for the symptomatic management of ulcerative colitis.
Conducted a randomized, double-blind, placebo-controlled, parallel-group pilot study.
Administered a cannabidiol-rich botanical extract versus placebo in patients with ulcerative colitis.
The primary endpoint was not reached during the trial.
Qualitative signals indicate that the cannabidiol-rich extract may provide symptomatic benefit in ulcerative colitis.

Cite This Study

Irving et al. (2018) studied this question.

synapsesocial.com/papers/69d8345a61e2ce1627d18eab https://doi.org/10.1093/ibd/izy002

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Implication

Randomized double-blind trial finds potential symptomatic benefit from cannabidiol extract in ulcerative colitis, suggesting therapeutic value despite an unmet primary endpoint.

A Randomized, Double-blind, Placebo-controlled, Parallel-group, Pilot Study of Cannabidiol-rich Botanical Extract in the Symptomatic Treatment of Ulcerative Colitis

Discussion

Member takes

Implication

Key Points

Cite This Study

A Randomized, Double-blind, Placebo-controlled, Parallel-group, Pilot Study of Cannabidiol-rich Botanical Extract in the Symptomatic Treatment of Ulcerative Colitis

Discussion

Member takes

Implication

Key Points

Cite This Study

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