November 1, 1983CirculationOpen Access

Parasystole, reentry, and tachycardia: a canine preparation of cardiac arrhythmias occurring across inexcitable segments of tissue.

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Structured PICO

Population

Canine preparation consisting of a protected ectopic focus (Purkinje fiber with a narrow central inexcitable zone) excised from one heart interacting with the intact heart of another animal

Intervention

Alteration of atrial driving rate, level of block, or level of automaticity

Outcome

Arrhythmic expression (parasystole, modulated parasystole, reentry, and tachycardia)surrogate

Parasystole and reentry may share a common electrophysiological mechanism dependent on heart rate, block level, and automaticity in a canine model.

Discussion

No takes yet. Share an insight, caveat, or question.

Implication

Should not yet alter clinical arrhythmia classification; leaves open translation of shared parasystole-reentry mechanisms beyond canine models.

Cite This Study

Antzelevitch et al. (1983) studied this question.

synapsesocial.com/papers/69d83b0d617ce96c42ae3518 https://doi.org/10.1161/01.cir.68.5.1101

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Implication

Should not yet alter clinical arrhythmia classification; leaves open translation of shared parasystole-reentry mechanisms beyond canine models.