Small but significant diurnal variation occurs in the regional thickness and the shape of the anterior and posterior cornea. The largest changes in the cornea are typically evident upon waking. The regional corneal swelling observed at this time was not uniform, being slightly greater in peripheral corneal regions. The pattern of corneal swelling evident on waking resulted in a steepening of the posterior, and a flattening of the anterior corneal surface.
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Read et al. (2009) studied this question.
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