Why the study?
Do anticoagulants compared to aspirin reduce the recurrence rate in patients with cervical arterial dissection?
Do anticoagulants compared to aspirin reduce the recurrence rate in patients with cervical arterial dissection?
Preliminary data showing a high initial recurrence rate in cervical arterial dissection suggests a large-scale trial comparing anticoagulants and aspirin is feasible.
High recurrence supports feasibility of a 2000-patient RCT; leaves open optimal antithrombotic strategy in cervical dissection.
From our data indicating an initial relatively high recurrence rate, a multicenter trial of anticoagulants versus aspirin involving a total of 2000 patients is feasible.
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Beletsky et al. (2003) studied this question.
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